ASA Princeton-Trenton Chapter and ASA New Jersey Chapter Joint 2016 ASA Traveling Course

Dear fellow statisticians,

ASA Princeton-Trenton chapter and NJ chapter will jointly host the 2016 ASA traveling short course:

Statistical Issues in Design and Analysis of Pragmatic Clinical Trials

Instructor: Professor Andrea Troxel, Perelman School Of Medicine, University Of Pennsylvania

When: Friday, October 14, 2016, from 10:00 AM to 3:00 PM

Where:

East Lecture Hall, Rutgers Robert Wood Johnson Medical School

675 Hoes Lane West,

Piscataway, NJ 08854

How to Register:

Please use the following link for registration: http://asa2016travelcourse.eventbrite.com

Regular registration: $60; student/retiree: $30

Note that refreshments and a lunch buffet are included in each registration, and parking is complimentary and available in Lots A, B & C. Event Parking signage will be at the entrance to Lots A, B & C.

This is a great opportunity for learning and networking. We look forward to seeing you at this exciting event.

Yujun Wu

President, ASA Princeton-Trenton Chapter

Steve Ascher

President, ASA NJ Chapter

Course Abstract: There is increasing interest in exploring the comparative effectiveness of therapies for a wide range of conditions. Pragmatic clinical trials offer promise. Features of pragmatic trials include simplicity of interventions or treatments, limited eligibility criteria for participants, streamlined approaches to consent, contact with participants occurring within existing processes, and outcome data obtained through administrative sources such as existing electronic health records, claims data, or registries. Pragmatic trials must still include randomization as a fundamental tool to allow valid comparison of interventions. The desired features of pragmatic trials give rise to a number of design and analytic challenges. This course will review the structure of pragmatic trials, describe some of the special design issues, and offer new approaches to handle them. Examples from actual trials in biomedical research will be provided.

About the Instructor: Dr. Andrea B. Troxel is Professor and Associate Director of Biostatistics at University of Pennsylvania Perelman School of Medicine, Director of the Abramson Cancer Center's Biostatistics Core, Director of Biostatistics at the Leonard Davis Institute Center for Health Incentives and Behavioral Economics at Penn, and Senior Scholar in the Center for Clinical Epidemiology and Biostatistics. In addition to her extensive experience in the design, conduct, and analysis of all phases of clinical studies, she has published on missing data, sensitivity analyses, and the development of statistical methodology for analysis of clinical trials. Recently she has focused on issues in pragmatic clinical trials, including methods of consent, non-standard randomization, rapid-cycle innovation, and multiple comparisons. She is the author of more than 175 articles in the literature of statistical methodology, cancer, behavioral research, and other areas of medicine. Dr. Troxel is an elected Fellow of the American Statistical Association; Associate Editor of Statistics in Medicine, a premier journal in biomedical statistics; and serves on Data Safety Monitoring Boards (DSMBs) for randomized trials in cancer, cardiac devices, smoking cessation, and behavioral therapies. She has directed PhD dissertations in biostatistics and mentored numerous fellows in oncology, radiology, and general medicine.